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Manuel de la Mata

Biol. Col : 19989-M

Manuel de la Mata. Precision, Preventive and Personalized Medicine. Geneticist | Product Manager and genetic consultant at 24Genetics.

Manuel de la Mata, MsC. He is a young geneticist and genetic counselor, a biologist specialized in clinical genetics and fertility. Currently, he continues his active training, both self-taught and through institutions, symposia and international congresses.

He began his professional career rotating at the Ramón y Cajal Hospital, one of the pioneering hospitals in Spain in the area of clinical genetics. It was through this experience, when he learned and realized about the potential and passion that genetics held.

Subsequently, he made the leap to 24Genetics, in the early days of the company. His role has been focused on the product development and genetic counseling department for the last two years.

Manuel has been a member of several societies such as: The European Society of Human Genetics, the Spanish Society of Human Genetics and of the Spanish Society of Genetic Counseling.



  • Design, production and update of new genetic reports.
  • Development of algorithms
  • Genetic counseling (rare, complex and monogenic diseases, cancer, pharmacogenetics, nutrigenetics)
  • GWAS analysis




Clinical Genetics and Assisted Reproduction


Degree in Biology



Mapping the human genetic architecture of COVID-19

An individual's genetic makeup contributes to susceptibility and response to viral infection. Although environmental, clinical, and social factors play a role in SARS-CoV-2 exposure and severity of COVID-191,2 disease, host genetics may also be important. Identification of host-specific genetic factors may reveal therapeutically important biological mechanisms and elucidate causal relationships of modifiable environmental risk factors for SARS-CoV-2 infection and outcomes. We formed a global network of investigators to investigate the role of human genetics in SARS-CoV-2 infection and the severity of COVID-19. We describe the results of three genome-wide association meta-analyses covering up to 49,562 patients with COVID-19 from 46 studies in 19 countries. We report 13 significant genome-wide loci that are associated with SARS-CoV-2 infection or severe manifestations of COVID-19. Several of these loci correspond to previously documented associations with pulmonary or autoimmune and inflammatory diseases3-7. They also represent potentially actionable mechanisms in response to infection. Mendelian randomization analyses support a causal role for smoking and body mass index for severe COVID-19, although not for type II diabetes. The identification of novel host genetic factors associated with COVID-19, with unprecedented speed, was made possible by the human genetics research community coming together to prioritize the sharing of data, results, resources, and analytical frameworks. This model of international collaboration highlights the potential for future genetic discoveries in emerging pandemics or, indeed, any complex human disease.



  • 5th Conference on Genetic Counselling: Hospital Dexeus, Spain, 2019
  • Assisted Reproduction and Fertility Symposium - GINEFIV, Spain, 2018
  • CEGEN - Partnership studies: data design and analysis, Spain, 2018





Cardiovascular health

The heart organ is a powerful pump that circulates blood, nutrients and oxygen throughout the body and, surprisingly, is the first organ to form during embryonic development. In Greek medicine, it was considered the most important organ, and today, the fact that heart...

Cancer and Genetics

What is cancer? Cells are the basic units that make up the human body, and they grow and divide to create new cells as the body needs them, forming our organs and tissues. Usually, they die when they grow old or become too damaged, and new cells take their place [1]....

Genetics and diabetes

Types of diabetes Diabetes is a chronic metabolic disease that indicates that glucose levels in the blood are very high and, over time, erodes systems and organs such as kidneys or blood vessels (1). There are two types of diabetes: Type I diabetes, in which the...

Genetics and Alzheimer’s disease

Alzheimer's disease is one of the most common neurodegenerative disorders in the world. From the sixth decade of life, the risk begins to multiply (1). It is a progressive disease, currently without a cure, which manifests itself mainly in memory problems and is...

Nutrition and Covid19

If anything, 2020 has been filled with changes in our way of life, brought about by the pandemic. Personal health and wellness have emerged as the main objectives in times of COVID, and nutrition has become a critical factor in achieving and maintaining the desired...

Covid19 and 24Genetics: new developments part II

COVID-19 unites efforts in research Since the early days of the virus spread throughout the world, research at the international level also began. Proof of this is the different consortiums created to fight the pandemic, such as COVID-19 High-Performance Computing...

Covid19 and 24Genetics: new developments part I

From the beginning of the pandemic, 24Genetics had it clear that it wanted to do its part in the fight against COVID19. Over the last few months, we have made an enormous effort and worked on new lines of development and research.   24Genetics free pharmacogenetics...

Artificial intelligence

Over the past few years, we have experienced an exponential increase in data creation. From when our smartphone tells us how many steps we take, to count the times we get on public transport, to how many megabytes we spend on our mobile data rate.   Big data Just as...

24Genetics and transparency

Transparency had been one of the 24Genetics' main commitments since its birth three years ago. Our goal is for customers always to know what service they are contracting and what kind of information they can expect from it. Our genetic health test already covers more...

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