PACK ALL IN ONE
Our genetic information is key to making some of the most critical decisions in our lives. There are diseases that we can prevent, and the DNA Health Test can help us identify them.
Know your genetic predisposition with a DNA health test!
Prevention and early diagnosis can multiply success rates by 5 to 10 times in treating many diseases. Your genomics will tell you where to focus. By analysing your genetic map, we obtain essential information to make the best decisions regarding your health and well-being.
Download our sample Health report.
Reports available in English, French, Italian, Polish, Spanish and German.
Our genetic health report is possibly the most comprehensive DNA test on the market.
We analyse more than 720,000 genetic markers. From these, we extract results based on the most prestigious genetic research using complex algorithms.
We study the ancestral roots in the DNA. These constitute the genetic inheritance of the person and serve to be able to apply these algorithms correctly. The calculation of genetic predisposition may vary according to ethnic origin. For example, the risk of skin cancer is not calculated in the same way for a person of African origin as it is for a person of Scandinavian origin. 24Genetics is possibly the only company in Europe that performs this ancestral roots analysis before applying the algorithms correctly.
Our algorithm also allows us to analyse whether the DNA belongs to a man or a woman.
In this way, we can apply the research that best suits each individual.
The reports we provide offer as much practical information as possible from the genetic data available in the test. For many diseases, we report the pathogenic mutations, or lack thereof, of only part of the genes involved (the ones we can see in the test). This means that the disease may be present in areas that we are not testing for. The genetic information provided by 24Genetics is not valid for clinical or diagnostic use. If any of your doctors or health professionals are especially concerned about a particular mutation detected, they will prescribe a second genetic test for clinical use to confirm these mutations. The 24Genetics tests serve, among other things, to bring to light very relevant information that is usually overlooked.
An example of a 24Genetics health test result report is available on this page.
Genetics gives us a lot of information.
And the 24Genetics DNA Test offers 7 detailed reports with multiple data for each of these 7 categories. We should not confuse talent or personal characteristics with pathologies or diseases. In particular, our DNA Health Test provides an exclusive health report. Detailing a multitude of diseases and accompanied by information on drug compatibility.
With the 24Genetics DNA Health Test, you can get an overview of a large number of pathologies at an affordable price. Thanks to these tests and as a genetic counsellor, we can be a valuable approach to understanding your genes. If you need a diagnosis of a specific disease, there are DNA tests that analyse the entire gene or genes involved in that disease or phenotype. These are also valid for clinical use. If you have a family history, we recommend that you consult your doctor or geneticist to consider the need for such a test.
With the knowledge of DNA, we can prevent the transmission of several monogenic diseases to our future children.
Some of these diseases may be present in our genes and not have manifested themselves in us. But it is possible that they may manifest in our children and grandchildren. With our DNA Health Test, we can identify many of them and act accordingly. In addition, there are techniques to prevent some of these diseases from being passed on to our offspring.
But having our genetic information can also be the first step towards personalised medicine. Each person should receive medical treatments in a different way. Medicines that are very effective for some people are not effective for others. One of the keys to deciphering which treatments will be best for each person lies in their genes. Our DNA Health Test includes data on genetic predisposition to dozens of medications. It can therefore help your doctor prescribe the most appropriate drugs for you. The importance of a genetic counsellor like 24Genetics Spain is essential for your genetic analysis and personalised medicine.
24Genetics DNA tests are preventive.
We perform the tests by analysing a part of the genetic variants of the organism (about 720,000 out of a total of 3.2 billion). Therefore, they have no clinical or diagnostic validity. Having a predisposition to suffer from a disease or pathology does not mean that you will definitely suffer from it. Many other external (environmental) and lifestyle factors play a role. Similarly, a disease for which no predisposition is indicated may develop.
Furthermore, there may be mutations in gene regions that we do not analyse. For this reason, at 24Genetics, we always recommend consulting a medical professional or geneticist to go deeper into specific areas, especially when there is a family history. And to carry out a diagnostic DNA test, in case the professionals recommend it.
What will you find in the 24Genetics Health Report?
We analyse your genetic predisposition to hundreds of diseases, grouped into the following types:
Complex Diseases: GWAS
For this part of our report, we apply GWAS publications, a type of study that compares the DNA markers of people with a disease with people without the disease in order to identify genetic differences. These studies can be beneficial for prevention and early diagnosis, as they are not a diagnostic tool but indicate what to look out for.
It is essential to bear in mind that many factors influence complex diseases, genetics being only one part; lifestyle, diet, etc… are in many cases the most influential.
Complex diseases: mutations
In this section, we analyse the mutations of the most important genes from an oncological point of view. We specifically look for mutations reported as pathogenic in the main scientific communities.
Biomarkers, biometrics and traits
In this section, we again use GWAS statistical analyses to calculate your genetic predisposition to have abnormal levels of specific metabolic parameters.
We analyse genetic mutations that can cause inherited diseases that can be transmitted to your future children. You can be a carrier of some of them and never have suffered from them, but there is a risk that your future offspring will suffer from them. These are primarily single-gene diseases.
Genetic testing for hereditary diseases of both the future father and the future mother before the baby is conceived is the smartest move to minimise the chances of our children suffering from such diseases. If such diseases run in your family, genetic testing is essential. With the data in hand, a geneticist will be able to give you guidelines on how to act. If you want to know more about this subject, read our blog article “How genetics can help you have healthier children”.
We will analyse the mutations that predispose us to feel better or worse when using certain drugs, and this will help our doctors to choose the most suitable ones for us. So your pharmacological analysis will be your first step towards personalised medicine.
24Genetics genetic tests are not valid for clinical or diagnostic use. However, if your doctor considers a mutation found in our reports to be relevant, the usual practice is to prescribe a specific genetic diagnostic test to corroborate these mutations.
These are some of the diseases you will find in our report:
|Alopecia areata||Kabuki Syndrome 1|
|Intracranial aneurysm||Leigh Syndrome|
|Rheumatoid arthritis||Leopard Syndrome 1|
|Asthma (childhood onset)||Leukoencephalopathy With Vanishing White Matter|
|Chronic bronchitis and chronic obstructive pulmonary disease||Lissencephaly 1|
|Breast cancer||Loeys-Dietz Syndrome 2|
|Non-melanoma skin cancer||Long Qt Syndrome 1|
|Prostate cancer||Maple Syrup Urine Disease|
|Prostate cancer aggressiveness||Maturity-Onset Diabetes Of The Young, Type 2|
|Prostate cancer (early onset)||Maturity-Onset Diabetes Of The Young, Type 3|
Meckel Syndrome, Type 3
|Upper aerodigestive tract cancers||Mental Retardation And Microcephaly With Pontine And Cerebellar Hypoplasia|
|Basal cell carcinoma||Metachromatic Leukodystrophy|
|Squamous cell carcinoma||Methylmalonic Aciduria And Homocystinuria, Cblc Type|
|Motion sickness||Methylmalonic Aciduria, Cbla Type|
|Primary biliary cirrhosis||Methylmalonic Aciduria, Cblb Type|
|Age-related macular degeneration||Mitochondrial Complex Iii Deficiency, Nuclear Type 1|
|Conduct disorder||Mucopolysaccharidosis Type Vi|
|Type 1 diabetes||Mucopolysaccharidosis, Type Vii|
|Type 1 diabetes nephropathy||Mucopolysaccharidosis, Type Iiia|
|Type 1 diabetes autoantibodies||Mucopolysaccharidosis, Type Iiib|
|Type 2 diabetes||Mucopolysaccharidosis, Type Iva|
|Endometriosis||Muscular Dystrophy-Dystroglycanopathy (Congenital With Brain And Eye Anomalies), Type A, 1|
|Celiac disease||Myopathy, Myofibrillar, 1|
|Alzheimer’s disease (late onset)||Myopathy, Centronuclear, X-Linked|
|Coronary heart disease||Myopathy Centronuclear|
|Parkinson’s disease||Nemaline Myopathy 2|
|Multiple sclerosis||Cystinosis, Nephropathic|
|Niemann-Pick Disease, Type C1|
|Schizophrenia||Niemann-Pick Disease, Type A|
|Glioma||Niemann-Pick Disease, Type B|
|Hypothyroidism||Noonan Syndrome 1|
|Myocardial infarction (early onset)||Noonan Syndrome-Like Disorder With Or Without Juvenile Myelomonocytic Leukemia|
|Chronic lymphocytic leukemia||Noonan Syndrome 4|
|Hodgkin’s lymphoma||Obesity Due To Melanocortin 4 Receptor Deficiency|
|Diffuse large B cell lymphoma||Albinism, Oculocutaneous, Type Ib|
|Follicular lymphoma||Osteogenesis Imperfecta, Type Iii|
|Myasthenia gravis||Diabetes Mellitus, Permanent Neonatal|
|Multiple myeloma||Pitt-Hopkins Syndrome|
|Neuroblastoma||Polymicrogyria, Bilateral Frontoparietal|
|Osteosarcoma||Microcephaly 3, Primary, Autosomal Recessive|
|Psoriasis||Microcephaly 5, Primary, Autosomal Recessive|
|Allergic sensitization||MICROCEPHALY 9, PRIMARY, AUTOSOMAL RECESSIVE; MCPH9|
|Testicular germ cell tumor||Retinitis Pigmentosa|
Rubinstein-Taybi Syndrome 1
|Vitiligo||Sotos Syndrome 1|
|17-Beta Hydroxysteroid Dehydrogenase Iii Deficiency||Supravalvular Aortic Stenosis|
|3-Methylcrotonyl-Coa Carboxylase 1 Deficiency||Tay-Sachs Disease|
|3-Methylcrotonyl-Coa Carboxylase 2 Deficiency||Tuberous Sclerosis 1|
|Aarskog-Scott Syndrome||Tuberous Sclerosis 2|
|Achromatopsia 2||Albinism, Oculocutaneous, Type Ia|
|Leukemia, Acute Myeloid||Tyrosinemia, Type I|
|Adrenoleukodystrophy||Usher Syndrome, Type I|
|Hypophosphatasia, Adult||Usher Syndrome, Type Id|
|Allan-Herndon-Dudley Syndrome||Usher Syndrome, Type If|
|Alpha-1-Antitrypsin Deficiency||Usher Syndrome, Type Iia|
|Amyloidosis, Hereditary, Transthyretin-Related||Usher Syndrome, Type Iic|
|Anemia, Nonspherocytic Hemolytic, Due To G6Pd Deficiency||Usher Syndrome, Type Iid|
|Angelman Syndrome||Usher Syndrome, Type Iiia|
|Antithrombin Iii Deficiency||Acyl-Coa Dehydrogenase, Very Long-Chain, Deficiency Of|
|Arrhythmogenic Right Ventricular Dysplasia, Familial, 10||Weaver Syndrome|
|Auriculocondylar Syndrome 1||Wilson Disease|
Hypophosphatemic Rickets, Autosomal Dominant
|Bardet-Biedl Syndrome 1||Severe Combined Immunodeficiency, X-Linked|
|Muscular Dystrophy, Becker Type||Adiponectin levels|
|Seizures, Benign Familial Neonatal, 1||Alcoholism (alcohol dependence factor score)|
|Bloom Syndrome||Aortic root size|
|Brugada Syndrome 1||Beta-2 microglubulin plasma levels|
|Cardiofaciocutaneous Syndrome 1||Bilirubin levels|
|Cardiofaciocutaneous Syndrome 1||Bone mineral density|
|Cardiomyopathy, Dilated, 1S||C-reactive protein|
|Cardiomyopathy, Familial Hypertrophic, 1||Calcium levels|
|Ceroid Lipofuscinosis, Neuronal, 1||Dehydroepiandrosterone sulphate levels|
|CEROID LIPOFUSCINOSIS, NEURONAL, 2; CLN2||Eosinophil counts|
|Ceroid Lipofuscinosis, Neuronal, 7||Spirometric measure of pulmonary function (Forced vital capacity)|
|Charcot-Marie-Tooth Disease, Type 4C||Glycated hemoglobin levels|
|Chondrodysplasia Punctata 1, X-Linked Recessive||Glycerophospholipid levels|
|Granulomatous Disease, Chronic, X-Linked||Heart rate|
|Adrenal Hypoplasia, Congenital||Homocysteine levels|
|Retinitis Pigmentosa 39||IgE levels|
|Night Blindness, Congenital Stationary, Type 1C||Liver enzyme levels (gamma-glutamyl transferase)|
|Cornelia De Lange Syndrome 1||Liver enzyme levels|
|Costello Syndrome||Magnesium levels|
|Cystic Fibrosis||Menopause (age at onset)|
|Danon Disease||Monocyte count|
|DEAFNESS, AUTOSOMAL RECESSIVE 12; DFNB12||Neutrophil count|
|Deafness, Autosomal Recessive 1A||
Phospholipid levels (plasma)
|Deafness, Autosomal Recessive 31||Phosphorus levels|
|Deafness, Autosomal Recessive 7||Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid)|
|Deafness, Autosomal Recessive 9||Platelet count|
|Mannosidosis, Alpha B, Lysosomal||Red blood cell count|
|Cardiomyopathy, Dilated, 1A||Resting heart rate|
|Dubin-Johnson Syndrome||Serum albumin level|
|Epileptic Encephalopathy, Early Infantile, 2||Serum total protein level|
|Emery-Dreifuss Muscular Dystrophy 1, X-Linked||Sex hormone levels|
|Myoclonic Epilepsy Of Lafora||Smoking behavior|
|Erythrocytosis, Familial, 2||Thyroid hormone levels|
|Fabry Disease||Uric acid levels|
|Familial Adenomatous Polyposis 1||Urinary uromodulin levels|
|Cardiomyopathy, Familial Hypertrophic, 2||Vitamin B levels in ischemic stroke|
|Familial Mediterranean Fever||White blood cell count|
|Thyroid Carcinoma, Familial Medullary||APC: colorectal and pancreatic cancer|
|Fanconi Anemia, Complementation Group A||ATM: breast cancer|
|Fanconi Anemia, Complementation Group O||BARD1: breast cancer|
|Nephrotic Syndrome, Type 1||BRCA1: breast and ovarian cancer|
|Gaucher Disease, Type I||BRCA2: breast and ovarian cancer|
|Glycogen Storage Disease Ib||BRIP1: breast cancer|
|Glut1 Deficiency Syndrome 1||CDH1: breast and gastric cancer|
|Glutaric Acidemia I||CDKN2A: pancreatic cancer|
|Multiple Acyl-Coa Dehydrogenase Deficiency||CHEK2: breast and colorectal cancer|
Glycogen Storage Disease Ia
|MLH1: Lynch syndrome|
|Glycogen Storage Disease Ii||MSH2: Lynch syndrome and colorectal cancer|
|Hemophagocytic Lymphohistiocytosis, Familial, 2||MSH6: Lynch syndrome and colorectal cancer|
|Hermansky-Pudlak Syndrome 3||MUTYH: MYH-associated polyposis and colorectal cancer|
|Histiocytosis-Lymphadenopathy Plus Syndrome||PALB2: breast and pancreatic cancer|
|Ectodermal Dysplasia 1, Hypohidrotic, X-Linked||PMS2: Lynch syndrome and colorectal cancer|
|Jervell And Lange-Nielsen Syndrome 1||PTEN: breast, uterine and colorectal cancer|
Joubert Syndrome 10
RAD51C: ovarian cancer
|Joubert Syndrome 14||RAD51D: ovarian cancer|
|Joubert Syndrome 16||SDHB: gastric cancer|
|Joubert Syndrome 3||SMAD4: juvenile polyposis syndrome and colorectal cancer|
|Joubert Syndrome 5||TP53: Li-Fraumeni syndrome, breast cancer and more|
|Joubert Syndrome 7||VHL: Von Hippel-Lindau syndrome|
|Joubert Syndrome 8||RET: thyroid carcinoma|
|Joubert Syndrome 9|