This 24Genetics Health Report could make a real difference in your wellbeing
Our genetic information is key to making some of the most important decisions in our lives. There are diseases that can be prevented if we act in time, and our DNA can help us to identify them. Prevention and early diagnosis can multiply success ratios by 5 to 10 times. Your genomics will tell you what you should focus on. By analysing your genetic map, we obtain important information so that you can make the best decisions regarding your health and wellbeing..
There is lot of useful information in this Genetic Test, giving you the opportunity to prevent the transmission of several monogenic diseases to your future children. Some of these diseases may be present in your genes and, even if you do not suffer them, they may develop in your children or grandchildren. With the genetic map, we can identify some of them, so we can prevent them, or you can enjoy the peace of mind of knowing that you do not carry those genes. Your genetic map will also help your doctor to prescribe the most suitable drugs, because you will know which ones are best for you, based on your genetic predisposition.
This 24Genetics Panel is one of the most advanced tests on the market. It employs the latest Illumina technology, and is able to give us a great amount of information, with a high degree of reliability.
This gene panel is, without a doubt, the best value for your money. We analyse 700,000 genetic markers covering the scientific community’s most important findings. In addition, we also examine many genetic markers that are now the subject of research, and that will be backed by scientific evidence in the coming months or years. Thus, you can sequence your genes today, and the data extracted will be valid and valuable not just today, but tomorrow too.
At a much lower price than that for complete genome sequencing, this genetic test offers the analysis of genetic markers for more than 200 diseases, genetic predisposition to dozens of medicines, and a wealth of information pertinent to your health care.
Most of the Gene Panels that one can find on the market are based on 2,500 to 5,000 genetic markers, while our new 24Genetics Panel analyses 700,000.
At this point in time, we have not found any more complete genetic test at this price.
The 24Genetics DNA Health Test report includes the following sections:
We analyse your genetic predisposition to more than 200 diseases, grouped into these types:
Genetic Health Risks: Gwas
In this part we apply GWAS publications, a type of study that compares the DNA markers of people with a disease or trait, to people without this them. These studies can be very useful for prevention and early diagnosis. It is not a diagnostic tool, but it helps one to see where he needs to be more careful, indicating his predisposition compared to the rest of the population.
Genetic Health Risk: mutations
In this section we analyse the mutations of the most important genes from the oncological point of view. We look for mutations suspected of being pathogenic, specifically those reported as pathogenic in the ClinVar database.
Hereditary diseases are likely to be passed on to your offspring. In most cases we can be carriers, and never suffer the disease, but there is a risk that our offspring will suffer them if certain conditions exist. These are mostly monogenic diseases. In this group we are looking for pathogenic mutations, or likely pathogenic mutations, in the genes involved in these diseases. We look for the mutations that are reported in some of the most important genetic databases worldwide, primarily the OMIM and ClinVar. In the event that you have this kind of mutation, or inheritable diseases in your family, taking this kind of genetic test is very important. With the DNA data, a geneticist can give you guidelines on how to act.
Biomarkers, biometrics and traits
In this section we use, again, the GWAS statistical analysis to calculate your genetic predisposition to present abnormal levels of certain metabolic parameters. We will tell you what your genes indicate that you have to be careful with. There are mutations that predispose one to have abnormal cholesterol or triglyceride levels, or other important parameters, so you can monitor them more closely. You can also view your predisposition to the effects of alcohol, caffeine and more
We will analyse the mutations that predispose you to having certain medications work well or not in your body. This will help your doctors to choose the right medicines for you. Your pharmacological analysis will be your first step into personalised medicine.
The genetic information provided by 24genetics is valid only for research, information and educational uses. In no case is it valid for clinical use.
At 24Genetics we advise all our customers to schedule a Genetic Advice Consultation in order to ensure a proper understanding of the DNA Reports and get the most out of them.
Questions and answers
We send our DNA kits to any country in the world. You can choose free regular shipping by post, or Express Shipping (round trip). We have many warehouses worldwide, so we will ship from the closest point possible. Europe and USA feature free Express Shipping. Some Packs offer free Express Shipping worldwide
It is really simple. We will home deliver a DNA KIT to you. You will receive a small cotton swab that you simply rub inside your mouth. Watch this video before using the kit: Click here to see the video. After following a few simple instructions, send us the swab back. At a specialised laboratory, we extract the DNA from the sample that you have sent us, and we carry out a process in which we can read what is written in some 700,000 markers of your DNA. After a complex computer analysis, our algorithms apply the latest genetic studies to generate the report that we place in your hands.
No. Any changes you plan to make regarding your health should be analysed by an expert geneticist and specialised doctors. Any questions you have about any genetic test should be posed to healthcare personnel expert in Genetic Diagnosis.
No. Your body responds to a whole range of conditions. Our genes are certainly an important parameter, but lifestyle, exercise, diet, and many other circumstances influence our bodies. Knowing yourself well certainly helps to treat your body in the most appropriate way. And this is what you can get from genetics: more knowledge.
No. Our genetic test is, possibly, the most complete on the market. There are some simple genetic tests that can only give you a small amount of information. Our genetic test is based on latest-generation genetic sequencing, allowing us to analyse about 700,000 genetic markers.
This test is based on different genetic studies that are internationally recognised and accepted by the scientific community. There are certain scientific organizations and databases where studies are published when there exists a certain level of consensus. Our genetic tests are carried out by applying these studies to our customers’ genetic information. Below you can see some of these studies used in this genetic test.
- Ahmed S et al; Newly discovered breast cancer susceptibility loci on 3p24 and 17q23; Nat Genet; 2009 May;41(5):585-90.
- Cox A et al; A common coding variant in CASP8 disassociated with breast cancer risk; Nat Genet; 2007 Mar;39(3):352-8.
- Dickson C et al; Tyrosine kinase signalling in breast cancer: fibroblast growth factors and their receptors; Breast Cancer Res; 2000;2(3):191-6.
- Easton DF et al; Genome-wide association study identifies novel breast cancer susceptibility loci; Nature; 2007 Jun28;447(7148):1087-93.
- Libioulle C et al; Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4; PLoS Genet; 2007 Apr 20;3(4):e58.
- McCarroll SA et al; Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn disease; Nat Genet; 2008 Aug 24.
- Ogura Y et al; A frameshift mutation in NOD2 associated with susceptibility to Crohn disease; Nature; 2001 May 31;411(6837):603-6.
- Parkes M et al; Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn disease susceptibility; Nat Genet; 2007 Jul;39(7):830-2.