This 24Genetics Health Report could make a real difference in your wellbeing.
Our genetic information is key to making some of the most important decisions in our lives. Some diseases we can prevent if we act in time, and our DNA can help us to identify them. Prevention and early diagnosis can multiply success ratios by 5 to 10 times. Your genomics will tell you where you should focus. By analyzing your genetic map, we obtain essential information so that you can make the best decisions regarding your health and wellbeing.
Reports available in English, German, French, Italian, and Spanish
There is a lot of useful information in this Genetic Test, giving you the opportunity to prevent the transmission of several monogenic diseases to your future children. Some of these diseases may be present in your genes and, even if you do not suffer them, they may develop in your children or grandchildren. With the genetic map, we can identify some of them so that we can prevent them, or you can enjoy the peace of mind of knowing that you do not carry those genes. Your genetic map will also help your doctor to prescribe the most suitable drugs, because you will know which ones are best for you, based on your genetic predisposition.
This 24Genetics Panel is one of the most advanced tests on the market. It employs the latest Illumina technology and can give us a considerable amount of information, with a high degree of reliability.
This gene panel is, without a doubt, the best value for your money. We analyze 700,000 genetic markers covering the scientific community’s most important findings. Furthermore, we also examine many genetic markers that are now the subject of research, and that will be endorsed by scientific evidence in the coming months or years. Thus, you can sequence your genes today, and the data extracted will be valid and valuable not just today, but tomorrow too.
At a much lower price than that for complete genome sequencing, this genetic test offers the analysis of genetic markers for more than 200 diseases, genetic predisposition to dozens of medicines, and a wealth of information pertinent to your health care.
Most of the Gene Panels that one can find on the market rely on 2,500 to 5,000 genetic markers, while our new 24Genetics Panel analyses 700,000.
At this point in time, we have not found any more complete genetic test at this price.
The 24Genetics DNA Health Test report includes the following sections:
We analyse your genetic predisposition to more than 200 diseases, grouped into these types:
(click here to see the list of diseases)
Genetic Health Risks: Gwas
In this part, we apply GWAS publications, a kind of study that compares the DNA markers of people with a disease or trait, to people without this them. These studies can be beneficial for prevention and early diagnosis. It is not a diagnostic tool, but it helps one to see where he needs to be more careful, indicating his predisposition compared to the rest of the population.
Genetic Health Risk: mutations
In this section, we analyse the mutations of the most important genes from the oncological point of view. We look for mutations suspected of being pathogenic, specifically those reported as pathogenic in the ClinVar database.
Carrier Status
Hereditary diseases are likely to be passed on to your offspring. In most cases, we can be carriers, and never suffer the disease, but there is a risk that our progeny will suffer them if certain conditions exist. These are mostly monogenic diseases. In this group, we are looking for pathogenic mutations, or likely pathogenic mutations, in the genes involved in these diseases. We look for the mutations that are reported in some of the most important genetic databases worldwide, primarily the OMIM and ClinVar. In the event that you have this kind of mutation or inheritable diseases in your family, taking this kind of genetic test is very important. With the DNA data, a geneticist can give you guidelines on how to act.
Biomarkers, biometrics, and traits
In this section we use, again, the GWAS statistical analysis to calculate your genetic predisposition to present abnormal levels of certain metabolic parameters. We will tell you what your genes indicate that you have to be careful with. There are mutations that predispose one to have abnormal cholesterol or triglyceride levels, or other important parameters so that you can monitor them more closely. You can also view your predisposition to the effects of alcohol, caffeine and more
Pharmacogenetics
We will analyse the mutations that predispose you to have certain medications work well or not in your body. This will help your doctors to choose the right medicines for you. Your pharmacological analysis will be your first step into personalised medicine.
The genetic information provided by 24genetics is valid only for research, information and educational uses. In no case, the test information is valid for clinical use.
At 24Genetics we advise all our customers to schedule a Genetic Advice Consultation to gain a proper understanding of the DNA Reports and get the most out of them.
Download our DNA Health Report Sample
Reports available in English, German, French, Italian and Spanish
Questions and answers
WHAT IS THIS TEST BASED ON?
This test is based on different genetic studies that are internationally recognised and accepted by the scientific community. There are certain scientific organizations and databases where studies are published when there exists a certain level of consensus. Our genetic tests are carried out by applying these studies to our customers’ genetic information. Below you can see some of these studies used in this genetic test.
- Ahmed S et al; Newly discovered breast cancer susceptibility loci on 3p24 and 17q23; Nat Genet; 2009 May;41(5):585-90.
- Cox A et al; A common coding variant in CASP8 disassociated with breast cancer risk; Nat Genet; 2007 Mar;39(3):352-8.
- Dickson C et al; Tyrosine kinase signaling in breast cancer: fibroblast growth factors and their receptors; Breast Cancer Res; 2000;2(3):191-6.
- Easton DF et al; Genome-wide association study identifies novel breast cancer susceptibility loci; Nature; 2007 Jun28;447(7148):1087-93.
- Libioulle C et al; Novel Crohn disease locus identified by genome-wide association maps to a gene desert on 5p13.1 and modulates expression of PTGER4; PLoS Genet; 2007 Apr 20;3(4):e58.
- McCarroll SA et al; Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn disease; Nat Genet; 2008 Aug 24.
- Ogura Y et al; A frameshift mutation in NOD2 associated with susceptibility to Crohn disease; Nature; 2001 May 31;411(6837):603-6.
- Parkes M et al; Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn disease susceptibility; Nat Genet; 2007 Jul;39(7):830-2.
