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Pharmacogenetics studies our predisposition to drugs. Thanks to this DNA analysis, we can determine the predisposition to a drug being toxic for us or simply ineffective.
Find out your genetic predisposition to drugs with a DNA test!
We have always observed how some drugs have the desired effect on some people but not on others. There can be many causes for these differences, and pharmacogenetics is undoubtedly one of the most important factors.
Our DNA pharmacogenetic tests analyze a list of drugs. We rely on recognized scientific studies with which we match your genetic data and obtain through our algorithms show us your predisposition to these drugs.
Download our example Pharmacogenetics report
Reports available in English, French, Italian, Polish, Spanish, German and Serbian.
Pharmacogenetics and pharmacogenomics: are they the same?
Pharmacogenetics and pharmacogenomics are words that are often used synonymously but have some differences. Pharmacogenetics is the biological discipline that studies the genetics of an individual’s response to drugs, while pharmacogenomics studies variation in the expression of disease-relevant genes and variable responses to certain drugs in order to develop new treatment pathways.
How can a pharmacogenetic test help me?
Currently, adverse drug reactions lead to significant morbidity and mortality in patients, often resulting in increased healthcare costs. Although drug compatibility has been known and studied for many decades and any package leaflet specifies the incompatibility of a drug with many others, genetics also has much to contribute with the pharmacogenetic tests. The assumption that patients are a homogeneous group of individuals and that medicines and treatments that are usually effective in one group of individuals will be effective in the rest is almost certainly wrong. Clinical experience shows that medicines that work very well in some patients have many side effects, are ineffective or cause adverse, even fatal, consequences in others. Pharmacogenetic tests are needed to find out.
Variations in drug response may be due to exogenous factors—for example, diet, consumption of coffee, tobacco, alcohol, other medicines, etc. But also endogenous factors such as age, gender and, importantly, genetics.
A drug can be administered by different routes, which will influence the speed of its effects, but in any case, it goes through a multitude of stages before reaching the tissue or organ for which it is indicated. It must be absorbed, metabolized, transported, degraded and excreted. At any of these steps, a variation in the sequence of a gene can interact with the drug and generate a different response than expected.
Thanks to pharmacogenetic analysis, we can know our predisposition to various drugs.
In this way, doctors can avoid those drugs that we know are likely to cause toxicity or simply will not have the desired effect. Doctors can choose the most effective drugs according to our genetics and calculate doses much more intelligently. For years, the Netherlands has been using the genetic information of its patients, who carry this data on their health cards. The pharmacy modulates medicines based on this personalized information.
Personalized medicine, also known as individualized medicine or genomic medicine, is medicine in which doctors try to prevent, diagnose or treat a disease, depending on its stage, using a patient’s genetic or biological information. It also becomes a fundamental element for saving costs (and time) in healthcare systems because the trial-and-error system is consistently reduced. We also speak of preventive medicine, when the criterion is more the moment of evolution of the disease, in this case, before it develops. There are medicines that, once prescribed, take months to be evaluated to find out whether they have the desired effect or not. In many cases, there are different pharmacological alternatives for the same pathology, and our doctor, having our pharmacological report, will have a better chance of getting it right “the first time”.
Our Pharmacogenetic DNA Analysis is divided into 5 medical specialities: cardiology, neurology, pain, oncology and others, and analyses predispositions to dozens of drugs.
These are some of the drugs we analyze
|Cardiology – Pravastatin
|Cardiology – Simvastatin
|Cardiology – Warfarin
|Cardiology – Phenprocoumon
|Cardiology – Hydrochlorothiazide
|Neurology – Amitriptyline
|Neurology – Bupropion
|Neurology – Citalopram
|Neurology – Clomipramine
|Neurology – Escitalopram
|Neurology – Carbamazepine
|Neurology – Aripiprazole
|Neurology – Clozapine
|Neurology – Haloperidol
|Neurology – Olanzapine
|Neurology – Paliperidone
|Neurology – Risperidone
|Neurology – Ziprasidone
|Neurology – Amisulpride
|Neurology – Quetiapine
|Oncology – Methotrexate
|Oncology – Vincristine
|Oncology – Cisplatin
|Oncology – Tamoxifen
|Oncology – Fluorouracil, capecitabine, pyrimidine analogues, tegafur and Neoplasms
|Oncology – Irinotecan
|Oncology – Mercaptopurine
|Others – Peginterferon Alpha-2b
|Others – Ribavirin
|Others – Tacrolimus
|Others – Sildenfail (Viagra)
|Others – Viagra (Sildenfail)
|Pain – Meperidine
|Pain – Morphine
|Pain – Pentazocine
|Pain – Aspirin
|Pain – Alfentanil
|Pain – Buprenorphine
|Pain – Fentanyl
|Pain – Naltrexone
|Pain – Tramadol